![]() See identical proteins and their annotated locations for NP_001269798.1 ![]() Location: 18 → 316 Ammonium_transp Ammonium Transporter Family The resulting isoform (4) has a shorter and distinct C-terminus compared to isoform 1. Status: REVIEWED Description Transcript Variant: This variant (4) lacks two alternate exons compared to variant 1, that causes a frameshift. See identical proteins and their annotated locations for NP_001269797.1 Location: 6 → 211 Ammonium_transp Ammonium Transporter Family Source sequence(s) AF037626, AK297151, AL928711 UniProtKB/TrEMBL B4DLT8, Q9UPC8 Conserved Domains (1) summary cl03012 This difference causes translation initiation at a downstream AUG and results in an isoform (3) with a shorter N-terminus compared to isoform 1. Status: REVIEWED Description Transcript Variant: This variant (3) uses an alternate splice junction at the 5' end of an exon compared to variant 1. Location: 18 → 312 Ammonium_transp Ammonium Transporter Family The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Status: REVIEWED Description Transcript Variant: This variant (2), also known as del789, lacks three alternate coding exons compared to variant 1. See identical proteins and their annotated locations for NP_001121163.1 NG_007494.1 RefSeqGene Range 5020.62956 Download GenBank, FASTA, Sequence Viewer (Graphics), LRG_796 This section to the one reported in Genomic regions, Identify version mismatches by comparing the version of the RefSeq in These reference sequences are curated independently of the genomeĪnnotation cycle, so their versions may not match the RefSeq versions in the current These reference sequences exist independently of genome builds. Expression Biased expression in bone marrow (RPKM 5.0), skin (RPKM 0.4) and 2 other tissues See more NEW Try the new Gene table ![]() Multiple transcript variants encoding different isoforms have been found for this gene. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. Full Name Rh blood group D antigen provided by HGNC Primary source HGNC:HGNC:10009 See related Ensembl:ENSG00000187010 MIM:111680 AllianceGenome:HGNC:10009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as RH Rh4 RH30 RhII RhPI DIIIc RHCED RHDel RHPII RhDCw CD240D HDFNRH RHXIII RHDVA(TT) RhK562-II Summary The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO.
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